Does this herald the use of immune checkpoint inhibitors (ICIs) as the standard neoadjuvant therapy for TNBC? Or do the risks outweigh the benefits? Healthcare professionals should report all serious adverse events suspected to be associated with the use of any medicine and device to FDA’s MedWatch Reporting System or by calling 1-80.26 July 2021 saw the US Food and Drug Administration (FDA) approval of the first immunotherapy agent – pembrolizumab – for use in combination with chemotherapy for the neoadjuvant treatment of high-risk, early-stage triple-negative breast cancer (TNBC). A description of FDA expedited programs is in the Guidance for Industry: Expedited Programs for Serious Conditions-Drugs and Biologics. Pembrolizumab received breakthrough therapy designation for this indication. This application was granted priority review. The FDA approved this application approximately 5 months ahead of the FDA goal date. This review used the Real-Time Oncology Review (RTOR) pilot program, which streamlined data submission prior to the filing of the entire clinical application, and the Assessment Aid, a voluntary submission from the applicant to facilitate the FDA’s assessment. View full prescribing information for Keytruda. Pembrolizumab is administered in combination with chemotherapy for neoadjuvant treatment for 24 weeks, and then as a single agent for adjuvant treatment for up to 27 weeks. The recommended dosage of pembrolizumab for TNBC is 200 mg every 3 weeks or 400 mg every 6 weeks as an intravenous infusion over 30 minutes. The most common adverse reactions reported in ≥ 20% of patients in trials of pembrolizumab in combination with chemotherapy were fatigue/asthenia, nausea, constipation, diarrhea, decreased appetite, rash, vomiting, cough, dyspnea, pyrexia, alopecia, peripheral neuropathy, mucosal inflammation, stomatitis, headache, weight loss, abdominal pain, arthralgia, myalgia, and insomnia. The pCR rate was 63% (95% CI: 59.5, 66.4) for patients who received pembrolizumab in combination with chemotherapy compared with 56% (95% CI: 50.6, 60.6) for patients who received chemotherapy alone. The main efficacy outcome measures were pathological complete response (pCR) rate and event free survival (EFS). Details of the chemotherapy regimen are in the drug label linked below. Patients were randomized (2:1) to pembrolizumab in combination with chemotherapy or placebo in combination with chemotherapy. Patients were enrolled regardless of tumor PD-L1 expression. The efficacy of pembrolizumab in combination with neoadjuvant chemotherapy followed by surgery and continued adjuvant treatment with pembrolizumab as a single agent was investigated in KEYNOTE-522 (NCT03036488), a randomized, multicenter, double-blind, placebo-controlled trial conducted in 1174 patients with newly diagnosed previously untreated high-risk early-stage TNBC (tumor size >1 cm but ≤2 cm in diameter with nodal involvement or tumor size >2 cm in diameter regardless of nodal involvement). The following trial was the basis of the neoadjuvant and adjuvant approval, as well as the confirmatory trial for the accelerated approval. FDA granted accelerated approval to pembrolizumab for this indication in November 2020. On July 26, 2021, the Food and Drug Administration approved pembrolizumab (Keytruda, Merck) for high-risk, early-stage, triple-negative breast cancer (TNBC) in combination with chemotherapy as neoadjuvant treatment, and then continued as a single agent as adjuvant treatment after surgery.įDA also granted regular approval to pembrolizumab in combination with chemotherapy for patients with locally recurrent unresectable or metastatic TNBC whose tumors express PD-L1 (Combined Positive Score ≥10) as determined by an FDA approved test.
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The extra $50 for the dedicated fax machine and phone line on the 7520 is prudent for home offices and individuals with higher-than-average fax volume, as the 7510 eFax version is a trial that only allows a maximum of 20 incoming and 20 outgoing pages per month, with the option to upgrade to an unlimited service for a monthly fee. HP partnered with eFax to bring fax functionality to HP's lower-end models - it works by sending a fax over the Internet so there's no worry of a busy signal to interrupt your transmission. The key difference between this model and the 7510 from last year is the latter lacked a dedicated fax machine, instead having an eFax companion utility. This model can also send scans directly to a PC, a memory card, a network folder, an e-mail message, or even the cloud. Regardless, its 1,200-dpi resolution scanned and copied crisply rendered documents. The standard flatbed scanner/copier measures 8.5 inches by 11.7 inches, but I was disappointed to find that the hardware omits a hinge that some may find necessary to scan thicker media such as books and multipage documents. The apps have potential, but prepare to battle long load times that require you to navigate through several submenu layers. It takes you directly to the store to download new apps, rate them, and even add your own comments. HP tells me that it plans to release a Software Development Kit (SDK) in the near future so software engineers can design their own shortcut apps for the store.Īdding apps to the 7520's home screen is as simple as hitting the Get More button. All the extra applications are free, and HP breaks them down into categories within the App Store: entertainment, home, kids, news/blogs, photo, and tickets.Įach one promises to streamline the printing experience by offering shortcuts to your favorite coupons, news articles, weather reports, recipes, and so on. The ePrintCenter is an online hub where you can view job history, change settings, add printers to your account, browse and install apps, and cancel print jobs. You can even create your own customized e-mail address. For another, it can't print Web pages, although you can simply copy and paste the text into a document as a workaround. It's really easy to set up, but there are a few restrictions.įor one, the printer must be on and also connected to your network. You can even navigate through the settings and change the e-mail address to an easier designation to give out to friends and family that you trust enough to take control of your printer - you can take ownership of that in the control panel (Wireless > Web Services > Display E-mail). In addition to Apple AirPrint, the 7520 also features HP's ePrint technology that lets you send jobs from any connected device to the printer using the uniquely assigned e-mail address. Macs and PCs alike on CNET's lab network were able to see the printer without the need to install any additional software. If keeping the network private from intrusive leeches is your concern, you can also manually input your network username and password details on the virtual QWERTY keyboard and the printer should immediately connect. HP's latest Auto Wireless Connect reduces the setup time to less than 2 minutes - if you make your network visible, that is. I tested the Wi-Fi connection process and found it simple to navigate through the initial setup screens, with help from the instructions on the driver disc. Still, I'm still not ready to see Ethernet printing extinguished entirely until wireless connectivity becomes more ubiquitous, and the gap will likely be a deal breaker for IT professionals shopping for a networked printer to connect an office. Unfortunately, HP omits an Ethernet port in an effort to push cloud printing features that can work only on a Wi-Fi network, which you should probably be using to reduce clutter anyway. Using AirPrint, you can print out a photo from your iPhoto library by simply choosing the connected printer and hitting Print. In addition to using a direct USB connection (like most vendors, HP does not include a USB cable with the printer), you can set up the Photosmart 7520 on your network via Wi-Fi, which also lets Apple users make an easy connection through AirPrint on a compatible iOS device. CPB 0517 - Breast Ductal Lavage and Fiberoptic Ductoscopy.CPB 0105 - Magnetic Resonance Imaging (MRI) of the Breast.CPB 0071 - Positron Emission Tomography (PET).Use of the MarginProbe for intra-operative margin assessment during breast surgery.Use of magnetic seeds (e.g., Magseed), and the SAVI SCOUT surgical guidance system during localized excisional biopsy or lumpectomy.Three-dimensional (3D) volumetric imaging and reconstruction of breast or axillary lymph node tissue.Other minimally invasive image-guided breast biopsy procedures (i.e., those not mentioned above) (e.g., PET-guided breast biopsy (Naviscan)).The following procedures are considered experimental and investigational because the effectiveness of these approaches has not been established: Vacuum assisted core-needle biopsy (Mammotome™ device).Īetna considers digital breast tomosynthesis-guided breast biopsy an equally acceptable alternative to mammographically guided biopsy for medically necessary indications.Ultrasound-guided core-needle biopsy or.Stereotactically guided core-needle biopsy or.Radioactive seed localization (RSL) or radio-guided occult lesion localization (ROLL) of non-palpable breast lesions for locating lesions to guide excisional biopsy or breast-conserving surgery or.Advanced Breast Biopsy Instrument (ABBI) or.This Clinical Policy Bulletin addresses breast biopsy procedures.Īetna considers any of the following minimally invasive image-guided breast biopsy procedures medically necessary as alternatives to needle localization core surgical biopsy (NLBx) in members with abnormalities identified by mammography that are non-palpable or difficult to palpate (i.e., because they are deep, mobile, small (less than 2 cm), or are composed of clustered microcalcifications): Number: 0269 Table Of Contents Policy Applicable CPT / HCPCS / ICD-10 Codes Background References Unique tournaments! Participate in tourneys with other players and get prizes. Play offline and online! You can enjoy our free puzzle games for adults offline (no wifi or internet connection required), but if you want to participate in online tournaments, be sure to check your internet or wifi. So if you are looking for addicting brain games, then “Clockmaker“ is what you need.I think it means he loves his wife and wishes they could just spend all of their time together with their kids and enjoy each other’s company. But he can’t do that cause he’s gotta work. The clockmaker reference is an allusion to double-talk of the album’s recurring theme (there’s nothing new/everything has already been done). A clockmaker doesn’t actually make clocks. He just takes a broken clock and makes it work/better. As an artist, Sturgill isn’t taking himself so seriously as to think he’s the first guy to do any of this or have any of these internal issues with being away from his family. Mars is the planet of war and he’s internally warring with doing what he loves while simultaneously missing those he loves. It’s also the fourth planet and this is his fourth album. Whether all of that is intentional or not is up to you. But sometimes happy accidents gain meaning long after they’ve been created because they simply fall in line with the concept regardless of intent. This may be far fetched but my interpretation of this is he is referencing his children as the clocks. I know, I know, this is out there but hear me out. The song starts out with him saying “I want to grow old with you in the Mountain View”. Obviously he is referencing his wife and being home with her enjoying life together. “I want to make babies til you say you’re through”. Follow the link below or visit your app store to update Clockmaker and play the new event 'Games of Ancients'. I believe he is talking about being the best dad and husband in the world that he has to now live in. An exciting competition with other societies for the Secrets of the Ancients is already waiting for you in the new version of the game. a clockmaker who sets in motion Brian Reed's trip to Woodstock in Bibb. He also says “some days I hate everything I am but your love holds a mirror to me. And they're tweeting, and they're YouTubing, and they're always on Facebook. This is by far the most powerful line of the whole song. How can you hate something that has shown so much love to someone else and is being given back to you unconditionally? In interviews he credits his wife many times with pushing him to follow his passion which resulted in his success. A success that has in many ways pulled him away from what he wants to be more than anything, a husband and a father. Her love is the only thing that keeps him going and helps him cope with not being there for them. He and his wife are creating life together starting the clock in a metaphorical sense and a literal sense.Ĭlock maker is a reference to there being a grand designer of all things living or AKA god. Personally, having children has made me become more aware of time than any other point in my life. You kind of gauge your age looking at your children. I’m constantly looking at them thinking where did the time go. When an egg and a sperm meet, the clock starts. I don’t know if this is where he is going with this but I like to believe this is it. Golomb et al.’s detailed analyses of order demonstrated that older adults have greater difficulty utilizing temporal context information and, furthermore, that older adults may try to rely on semantic information even when it is not helpful. One specific example of this was that the contiguity effect differed by age in free recall, younger adults tended to recall items together when these items had been originally presented together. Follow-up analyses examining the positions of the recalled items, relative to other items in the lists, revealed that older adults were less able to utilize order information. They found that older adults ( M = 73 years) showed greater declines in serial recall performance than the younger adults ( M = 20 years). study, younger and older adults’ free and serial recall of uncategorized word lists was examined. Very little research exists examining output serial order information in older adults (e.g., Golomb, Peelle, Addis, Kahana, & Wingfield, 2008 Maylor et al., 1999), and even less research exists investigating this important component of memory functioning in the oldest–old. Examining serial position curves in recall can provide additional information about strategic processes that participants may engage in during a task. Researchers examine the performance on each individual item within a list in a memory span task to look for trademark patterns of primacy (improved performance at the beginning of a list) and recency (improved performance at the end of a list). In the present study, we continued in this line of research by conducting an in-depth investigation of adult age differences in three measures of memory span, and extended previous research by including a large number of participants who fall into the age category of oldest–old (90 + years of age).Īdditionally, the use of serial position information has been central in the development of current theoretical views of working memory (Baddeley, 2007). Given the importance of WM to cognitive functioning, age-related differences have been investigated to improve our understanding of the causes of decline in WM performance (Craik & Bialystock, 2006 Dobbs & Rule, 1989). For example, the link between WM and reading comprehension is well-established (Daneman & Carpenter, 1980), as is the relationship of WM and general fluid intelligence (Gray, Chabris, & Braver, 2003 Salthouse & Pink, 2008). A number of important cognitive functions have been linked to WM processes. WM is considered an active portion of the memory system it is “a temporary storage system under attentional control that underpins our capacity for complex thought” (Baddeley, 2007, p. In recent years, there has been increasing interest in the role of working memory (WM) as a critical component of adult cognition (Babcock & Salthouse, 1990 Bopp & Verhaeghen, 2005). Implications of these findings for understanding strategic processing abilities in late life are discussed. Correlation analyses indicated the strongest negative correlation with age occurred with the size judgment span task. Participants’ recall patterns in the size judgment span task revealed that the two oldest groups of adults showed the largest decreases in recall performance across output serial positions, but did not differ significantly from each other. To test this hypothesis, we examined output serial position curves of recall data from three span tasks: forward and backward digit span and size judgment span. Previous research suggests that measures of working memory are more sensitive to age effects than are simple tests of short-term memory Bopp and Verhaeghen (Journal of Gerontology: Psychological Sciences 60:223–233, 2005), Myerson, Emery, White, and Hale, (Aging, Neuropsychology, and Cognition 10:20–27, 2003). In the present study, we examined adult age differences in short-term and working memory performance in middle-aged (45–64 years), young–old (65–74 years), old–old (75–89 years), and oldest–old adults (90 years and over) in the Louisiana Healthy Aging Study.
Meanwhile, the base is overthrown by a mutiny, attracting hordes of infected. Instead, they are detained in a military installation, where they learn that they are not immune and are actually asymptomatic carriers who have infected most of their rescuers. After answering a radio transmission (soldier voiced by David Scully), they make their final stand against hordes of infected before a military APC arrives to supposedly transport them to Northeast Safe Zone Echo, one of the few remaining safe areas. Following a series of train tracks, the group finally reaches a functioning but abandoned military evacuation point. Like the helicopter before it, this plane also crashes, and the survivors find themselves at the outskirts of the Allegheny National Forest. military had bombed the airport in an attempt to contain the infection, though the runway is partially intact, allowing the survivors to fuel up and escape in the waiting C-130 (pilot voiced by Gary Schwartz). Resting in a greenhouse, the survivors are interrupted by a military C-130 Hercules passing overhead, leading them to believe that it will land at the city's airport. Contacting a small fishing vessel (owner voiced by John Patrick Lowrie), they are kicked out of the boat at the city of Newburg across the river, finding much of it in flames. After encountering a paranoid and delirious man (voiced by Nathan Vetterlein) in the local church, they discover that the town is overrun and head to a boathouse for rescue. Finding an armored delivery truck, the group uses it to reach the small town of Riverside. Zoey is forced to kill him, causing the helicopter to crash in an industrial district outside the city. Fighting their way through the city's streets, subway, and sewers, they are rescued from the hospital's roof by the pilot (voiced by Dennis Bateman), only to discover that he is infected. Two weeks after the first infection, four immune survivors- Green Beret and Vietnam veteran William "Bill" Overbeck (voiced by Jim French), college student Zoey (voiced by Jen Taylor), district account manager Louis (voiced by Earl Alexander), and outlaw biker Francis (voiced by Vince Valenzuela)-make their way out of the city of Fairfield, only to discover that the infection is creating dangerous mutations in some of its hosts.Īfter narrowly avoiding the new types of infected, the survivors are alerted by a passing helicopter to an evacuation point at the roof of Mercy Hospital. Memorial walls-giving names and obituaries to those who have died in the infection-suggest that the game takes place in October 2009. Plot The survivors Francis, Bill, Zoey, and Louis (left to right) on the poster for the "No Mercy" campaignĪn outbreak of a highly contagious pathogen nicknamed the "Green Flu" (which causes extreme aggression, mutation to the body cells, loss of higher brain functions, and essential zombification of those who catch it) begins in Pennsylvania. In 2012, all Left 4 Dead campaigns were ported over to Left 4 Dead 2, with cross-platform multiplayer support between Windows and Mac versions of the game. The success of the game led to the development of the sequel Left 4 Dead 2, which was released in 2009. As was done with Team Fortress 2, Valve supplemented the game with free downloadable content. Considered one of the greatest video games ever made, the game won several publication awards, as well as distinctions from the Academy of Interactive Arts & Sciences and British Academy of Film and Television Arts. Left 4 Dead was well-received by the industry media upon its release, with praise for its replay value, focus on cooperative play, and cinematic feel, although some criticized its limited level selection and lack of narrative. In all modes, an artificial intelligence dubbed the " Director" controls level pacing and item placements in an attempt to create a dynamic experience and increase replay value. Left 4 Dead uses Valve's proprietary Source engine, with four game modes: a single-player mode in which allied characters are controlled by AI, a four-player co-op campaign mode, an eight-player online versus mode, and a four-player survival mode. Set during the aftermath of a zombie outbreak on the East Coast of the United States, the game pits its four protagonists, dubbed the "Survivors", against hordes of the infected. It was originally released for Microsoft Windows and Xbox 360 in November 2008 and for Mac OS X in October 2010, and is the first title in the Left 4 Dead series. Left 4 Dead is a 2008 first-person shooter game developed by Valve South and published by Valve. Install Screen Mirroring: LetsView on your Mac using the same steps for Windows OS above. Once Screen Mirroring is downloaded inside the emulator, locate/click the "All apps" icon to access a page containing all your installed applications including Screen Mirroring.The search will reveal the Screen Mirroring: LetsView app icon.Open the Emulator app you installed » goto its search bar and search "Screen Mirroring".On your computer, goto the Downloads folder » click to install Bluestacks.exe or Nox.exe » Accept the License Agreements » Follow the on-screen prompts to complete installation. Install the emulator on your PC or Mac:.Download Bluestacks Pc or Mac software Here >. We recommend Bluestacks because you can easily find solutions online if you run into problems while using it. Download an Android emulator for PC and Mac:.Liked Screen Mirroring? here are other Photo & Video apps like Screen Mirroring Samsung TV Screen Mirroring+ App Fire TV Stick Screen Mirroring LG TV Screen Mirroring + Cast Screen Mirroring to Mac & PC What's more, this feature can be used to mirror phone to phone, cast phone to PC, and stream PC to phone.ġ2. Even if it is not on the same WiFi network and place, the screen sharing between two devices can also be realized.ġ1. LetsView also offers the real-time whiteboard feature during the teaching process, which helps marking the key points in time.ġ0. In other words, LetsView enriches the methods of communication and entertainment and it also plays an indispensable role in our daily life.ĩ. Meanwhile, it also allows you to mirror computer screen to iPhone and iPad for recording and video mirroring.Ĩ. Documents, PowerPoint, and other teaching materials saved on the mobile phone can be quickly displayed on PC, Mac and smart TV.ħ. LetsView is a free screen mirroring tool that is compatible with multiple platforms.Ħ. When screen mirroring PC to phone, you can take full control of the computer screen with your fingers.ĥ. LetsView enables you to mirror iPhone/iPad to computer, TV, projector and other smart devices wirelessly.Ĥ. The main feature is to cast phone screen, as well as other smart devices to PC and TV.ģ. Let’s View a bigger world and enjoy it together 3. Video Mirroring The videos on Android, iOS device or any other DLNA streaming app can be easily streamed to TV using LetsView. You can share any content with your friends and family as you like. With this tool, you can broadcast your very own gaming content including PUBG Mobile, League of Legends, Call of Duty, Mobile Legends and more! The app makes it easy to share gameplay with your fans and keep wonderful moments on your phone and PC.Ģ. LetsView enables you to mirror your mobile phone, tablet and computer screen to TV with one click. But, the bathrooms are available year round. Unfortunately, the Exit Glacier Nature Center located at the trailhead closes on Labor Day in early September. First glimpse of Exit Glacier on the drive from Seward Alaska. But, if you make it to the End of Trail, you will literally be able to touch the icefield. This is a strenuous and difficult hike, with an elevation gain of close to 3000 feet. If you want to get up close and personal with Exit Glacier, though, I recommend hiking the 8.2 mile round trip Harding Icefields Trail. The 1.6 mile (one way) Glacier Overlook Loop Trail offers a great view and photo opportunity in front of Exit Glacier as well as sweeping views of the Outwash Plain and surrounding mountains. Get Up Close and Personal with Exit GlacierĮxit Glacier is located in the only portion of Kenai Fjords National Park that has road access. The Alaska DNR website has great tips on how to time our your hike to avoid getting stranded at the tide change. You cannot hike this portion of the trail during high tide. Pro Tip: Between Tonsina Point and Derby Cove, the trail is influenced by tide. Bring cash and exact change! Lowell Point State Recreation Site has several hiking trails along Resurrection Bay Pro Tip: Parking is available at the trailhead, but there is a $5 daily fee. Tonsina Point has beach access and campsites available. Fort McGilvray is home to World War II ruins and incredible views of Resurrection Bay. But, a shorter option is to hike 2.3 miles each way to Tonsina Point (follow Tonsina Trail signs). If you hike the entire trail, it’s 7.8 miles each way, out and back, taking you all the way to Fort McGilvray. The trailhead for the Caines Head Trail is located at Lowell Point State Recreation Site which is at the end of Lowell Point Road. There are several hikes just minutes from Downtown Seward offering gorgeous views of Resurrection Bay. Many tours stop for the season starting in mid to late May. Pro Tip: Check availability of tours and business hours of restaurants anytime from September to May. Don’t worry, I’ve done the work of finding what things to do are available in September for you! I’d be lying though if I said I didn’t have a little bit of FOMO about some of the activities that simply aren’t available in September. Although I was out adventuring early all day everyday, I left Seward feeling re-energized and relaxed. There’s something magical about this town in September. Here you’ll find shops, the SeaLife Center, and restaurants. Second, is Downtown, located on 3rd Avenue. This is where most of the water-based activities depart including glacier tours, kayaking, and fishing. First, is the Small Boat Harbor, located on 4th Avenue just one block off the Seward Highway. Most of the things to do in Seward are located in two main areas. The town of Seward is located on Resurrection Bay, which connects to the Gulf of Alaska. Whether you drive or take the train, the route takes you along the Seward Highway to the town of Portage where you merge onto State Highway 9 through the mountains and onto the Kenai Peninsula. Seward is located about 120 miles south of Anchorage. That means that if you purchase through a link, I may receive a small commission at no extra cost to you. In short, there are so many things to do in Seward Alaska in September and you can enjoy them all without the crowds.ĭisclosure: This post contains affiliate links. So, when Delta Airlines had an incredible fare sale to Alaska in September, I wondered what to do in Seward Alaska that time of year? Would anything be open? Would I regret my choice and have serious FOMO? But as the summer comes to an end, and the seasonal workers leave the area, the locals take a breath and many tour companies, restaurants and businesses close down for the winter or transition to their winter hours.Īll of this happens in mid to late September. It is the gateway to Kenai Fjords National Park, attracting droves of visitors seeking a taste of small town Alaska and a bit of adventure.ĭuring the summer months, the population of Seward nearly doubles as the town gears up for the busy tourist and commercial fishing season. Just 120 miles south of Anchorage, on the Kenai Peninsula, is the charming coastal town of Seward Alaska. If she held an apple-as some reports claim-it could mean she was Aphrodite, holding the award given to her by Paris before the Trojan War began. A spear could have meant one thing, a spool of thread another. With her arms long missing, would-be context clues have been lost for centuries. Still others have proposed she's Victory, or perhaps a prostitute. Some have suggested the sculpture is not Aphrodite/Venus, but Amphitrite, the sea goddess who was particularly adored on Milos. The inscription on the plinth-the slab on which the statue rested-that identified him as Venus de Milo's creator was lost nearly 200 years ago. Alexandros of Antioch is credited with her creation.Ī sculptor of the Hellenistic period, Alexandros is believed to have carved this masterpiece between 130 and 100 BCE. On April 8, 1820, a farmer named Yorgos Kentrotas came across the statue in pieces within the ruins of an ancient city on the island of Milos (formerly known as Melos). She's named in part for where she was discovered. Nonetheless, the Roman-inspired Venus de Milo caught on. However, the Greeks would have called this deity Aphrodite. It's popularly believed that this Grecian statue depicts the Greek Goddess of love and beauty, who was often rendered half-naked. Venus de Milo's title is a bit misleading. But there's much more to this iconic statue than a couple of absent appendages. (Also missing now is the metal jewelry scholars say decorated the statue’s arms, head and ears in ancient times, as well as the colored paint on its face, hair and drapery.) Speculation remains about the Venus de Milo’s original pose, although evidence suggests its once held an apple in its left hand.For much of the world, the mystery of the Venus de Milo lies in her missing arms. But, in fact, most scholars today believe the sculpture’s arms already were missing when it was found by Voutier and the farmer. Originally carved in two blocks of marble then fitted together, the statue stands 6 feet 7 inches from head to toe and is the creation of an artist named Alexandros of Antioch, about whom little is known.Īs for the Venus de Milo’s missing limbs, there long have been claims they were broken off in 1820 during a fight on the shore of Melos, as French and Turkish sailors vied for possession of the artwork. Now, however, the Venus de Milo is thought to have been produced around 100 B.C., during a later period known as the Hellenistic age. The Louvre initially promoted the Venus de Milo as a masterpiece from the Greek classical era. It arrived in France in 1821 and was presented to Louis XVIII, who donated it to the Louvre Museum, where it remains today. Voutier told his superiors about the discovery and the French acquired the artwork, which came to be known as the Venus de Milo, for a relatively modest sum. Recognizing the statue as potentially significant, the Frenchman, with the farmer’s help, unearthed its lower half not far away. Upon investigating, Voutier learned the farmer had located the top half of a statue of a woman. While digging near the ruins of an ancient theater, Voutier noticed that a local farmer, who’d been removing stones from a nearby wall for use as building materials, seemed to have found something inside the wall. An ensign in the French navy, Olivier Voutier, whose ship was anchored in the harbor at Melos, decided to kill time one day by going ashore and searching for antiquities. The artwork was discovered in 1820 on the Aegean island of Melos (also called Milos). One of the most famous examples of ancient Greek sculpture, the Venus de Milo is immediately recognizable by its missing arms and popularly believed to represent Aphrodite, the Greek goddess of love and beauty, who was known to the Romans as Venus. |
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